Jana Slobodnikova
Alexander Dubcek University of Trencin, Slovakia
Title: ANALYSES OF ROUTINELY TESTED TUMOR MARKERS, QUALITY CONTROL OF THE LABORATORY
Biography
Biography: Jana Slobodnikova
Abstract
Tumor markers are an important tools in laboratory diagnostics of cancer diseases, which allows us continual supervision of patients´ stage and its time-dynamics. Thanks to this laboratory parameters, recidiving diseases can be treated significantly earlier. In our study we evaluated routinely tested tumor markers CA125, Ca199, CEA, PSA, AFP, HCG and Ca153 with emphasis on their diagnostic value in clinical practice.
Aim
The goal of our preliminar study was to verify the informational quality of tested parameters in terms of precision, accuracy and reliability of results with the aim of the external quality control (EQC).
Material and methods
All listed tumor markers were determined by laboratory methods based on the principle of electrochemiluminescence. The anonymous material for the analysis was provided by a supplier of the external quality control in the form of sample pairs with an undisclosed concentration of the analyte.
After processing there were obtained concentrations of particular analytes and they were sent back to the supplier of external quality control for evaluation. Acceptable outcomes were cut-off values which didn´t exceed 20% of the CV of the group, to which laboratory methodologically belonged.