Jana Slobodnikova
Alexander Dubcek University of Trencin, Slovakia
Title: COMPARISON BETWEEN DIGITAL BREAST TOMOSYNTHESIS AND ULTRASOUND EXAMINATIONS
Biography
Biography: Jana Slobodnikova
Abstract
Breast cancer is the most common malignant disease in women worldwide. We compare the results of digital breast tomosynthesis ( DBT – digital 3D mamography , new technics methody with x- ray examinations ) ) as a screening and sonography (US) method, as a complementary method to mammography.
Objective: To compare the data obtained in the US and DBT within a retrospective study of women with histologically confirmed breast cancer.
Material and methods : We processed retrospective data of 916 patients examined at the Clinic of Radiology from 25 December 2015 to 31 January 2019. The age of patients was from 29 years to 86 years, median 53 years. Biopsy following DBT was indicated in 357 cases. Of these, 78 were positive, others were benign. In the group of malignant lesions, we compared the findings with the DBT. We evaluated lesions size, morphological character, vascularization, number of deposits, changes in gland architecture, number and presence of microcalcifications and changes in lymph node. In our retrospective study, we aimed to verify the cross-compliance and equivalence of results obtained by the two imaging techniques. We evaluated the data using MC Nemar's test using paired tests (parametric t-test and non-parametric Wilcoxon test). We have tested the relationship with Spearman's correlation coefficient
Results : The results are completed in the tables. The following results came from the comparison: Significant disagreement exists in visualization of vascularization, microcalcifications, even sizes, where e.g. DBT shows higher values, the methods also differ when comparing lesions by patient age. At age over 50 years, DBT is more accurate, compared to US at age 50 years. The low correlation of correspondence is also in the field of architectural changes. More accurate is the US.
Discussion: The disagreements of both methods are significant. And in all the retrospective study parameters. In women over 50 years of age, metastatic mammography is more accurate in the area of microcalcifications and changes in the area of lesions, bearing shapes are less suspect, and interstitial architecture is less convincing compared to US examinations. Women of younger age benefit from US, a combination of both modalities is essential. Both DBT and US are a complementary method to the golden standard of breast cancer screening - digital X-ray mammography. For suspicious and ambiguous images, both methods must be added, combined.
Conclusion: All statistical tests show that there are significant differences between the US and DBT methods in image processing of the same patient, and we can not accept the consistency of their imaging. We must accept their supplementation, combination.
Key words: breast cancer, sonography, digital breast tomography, correlation